Structure of PDB 7d4o Chain A

Receptor sequence
>7d4oA (length=346) Species: 550 (Enterobacter cloacae) [Search protein sequence]
MELQPQFNEFLANIRPTDTQKEDWKSGARTLRERLKNFEPLKEIVVSTFL
QGSIRRSTAIRPLGDKRPDVDIVVVTNLDHTRMSPTDAMDLFIPFLEKYY
PGKWETQGRSFGITLSYVELDLVITAIPESGAEKSHLEQLYKSESVLTVN
SLEEQTDWRLNKSWTPNTQVEDAPASEWKAHPLVLPDREKNEWGRTHPLA
QIRWTAEKNRLCNGHYINLVRAVKWWRQQNSEDLPKYPKGYPLEHLIGNA
LDNGTTSMAQGLVQLMDTFLSRWAAIYNQKSKPWLSDHGVAEHDVMARLT
AEDFCSFYEGIASAAEIARNALASEEPQESAQLWRQLFGSKFPLPG
3D structure
PDB7d4o Crystal structure and functional implication of a bacterial cyclic AMP-AMP-GMP synthetase.
ChainA
Resolution1.87 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP A S53 R56 D69 D71 Q210 Y250 V304 S53 R56 D69 D71 Q201 Y241 V295
BS02 ADP A Q51 R109 L194 R197 R204 T205 R307 Q51 R109 L185 R188 R195 T196 R298
BS03 MG A D69 D71 D69 D71
BS04 MG A D69 D71 D121 D69 D71 D121
BS05 MG A N258 L260 N249 L251
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0005525 GTP binding
GO:0016779 nucleotidyltransferase activity
GO:0046872 metal ion binding
Biological Process
GO:0009117 nucleotide metabolic process
GO:0051607 defense response to virus

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Molecular Function
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Biological Process
External links
PDB RCSB:7d4o, PDBe:7d4o, PDBj:7d4o
PDBsum7d4o
PubMed33836064
UniProtP0DSP4|CDND2_ENTH5 Cyclic AMP-AMP-GMP synthase (Gene Name=cdnD02)

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