Structure of PDB 7d1n Chain A

Receptor sequence
>7d1nA (length=325) Species: 6945 (Ixodes scapularis) [Search protein sequence]
LKWPRDLRPLAHHDLLYMGQISEDRGDFNATLRNFLVPRVVGSQKHREVR
EFIVRSLKDLDWDVEEDCFDGQTPHGIKPFCNVIATLNPSACHRLVLACH
YDSLLHKEGTFIGATDSAVPCAQLLYLARSLNGKLQNQKTRGDGLTLQLV
FFDGEEAFERWSSHDSLYGSRHLAQKWHEDRTSAERLESCLERSEIANQI
DRMEVMVLLDLLGAENPRFYSYFGETQPVYRRLVNIESRLNDAGLMELPR
RRRRTNYFSNSSTVGFIEDDHIPFLKRSVPIVHIIPSPFPDVWHTLDDNE
QNLHHPTISNLNKIFKAFVSEYLQL
3D structure
PDB7d1n A Unique Carboxylic-Acid Hydrogen-Bond Network (CAHBN) Confers Glutaminyl Cyclase Activity on M28 Family Enzymes.
ChainA
Resolution2.26 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.5: glutaminyl-peptide cyclotransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CU A D144 E184 H322 D116 E156 H294
BS02 CU A H128 D144 H100 D116
BS03 CU A H40 D41 K162 H13 D14 K134
BS04 CU A E296 H299 H311 E268 H271 H283
BS05 BCT A D144 D238 D116 D210
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding
GO:0016603 glutaminyl-peptide cyclotransferase activity
GO:0016746 acyltransferase activity
GO:0046872 metal ion binding
Biological Process
GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7d1n, PDBe:7d1n, PDBj:7d1n
PDBsum7d1n
PubMed33774034
UniProtB7QK46|QPCT_IXOSC Glutaminyl-peptide cyclotransferase (Gene Name=Qptc)

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