Structure of PDB 7cx1 Chain A

Receptor sequence
>7cx1A (length=602) Species: 1351 (Enterococcus faecalis) [Search protein sequence]
KGEMNLNALFIGDKAENGQLYKDLLIDLVDEHLGWRQNYMPQDMPVISSQ
ERTSKSYEKTVNHMKDVLNEISSRMRTHSVPWHTAGRYWGHMNSETLMPS
LLAYNFAMLWNGNNVAYESSPATSQMEEEVGHEFAHLMSYKNGWGHIVAD
GSLANLEGLWYARNIKSLPFAMKEVKPELVAGKSDWELLNMPTKEIMDLL
ESAEDEIDEIKAHSARSGKHLQAIGKWLVPQTKHYSWLKAADIIGIGLDQ
VIPVPVDHNYRMDINELEKIVRGLAEEQIPVLGVVGVVGSTEEGAVDSID
KIIALRDELMKDGIYYYVHVDAAYGGYGRAIFLDEDNNFIPYEDLQDVHE
EYGVFKEKKEHISREVYDAYKAIELAESVTIDPHKMGYIPYSAGGIVIQD
IRMRDVISYFDIPALLGAYILEGSKAGATAASVWAAHHVLPLNVAGYGKL
IGASIEGSHHFYNFLNDLTFKVGDKEIEVHTLTHPDFNMVDYVFKEKGND
DLVAMNKLNHDVYDYASYVKGNIYNNEFITSHTDFAIPDYGNSPLKFVNS
LGFSDEEWNRAGKVTVLRAAVMTPYMNDKEEFDVYAPKIQAALQEKLEQI
YD
3D structure
PDB7cx1 Crystal structure of a tyrosine decarboxylase from Enterococcus faecalis in complex with the cofactor PLP and inhibitor methyl-tyrosine
ChainA
Resolution2.54 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.1.1.-
4.1.1.25: tyrosine decarboxylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GKU A M99 N100 H241 T298 M92 N93 H234 T291
Gene Ontology
Molecular Function
GO:0004058 aromatic-L-amino-acid decarboxylase activity
GO:0004837 tyrosine decarboxylase activity
GO:0016830 carbon-carbon lyase activity
GO:0016831 carboxy-lyase activity
GO:0030170 pyridoxal phosphate binding
GO:0036468 L-dopa decarboxylase activity
Biological Process
GO:0019752 carboxylic acid metabolic process
GO:1903184 L-dopa metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:7cx1, PDBe:7cx1, PDBj:7cx1
PDBsum7cx1
PubMed
UniProtQ838D6|TYRDC_ENTFA L-tyrosine decarboxylase (Gene Name=tdc)

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