Structure of PDB 7cs1 Chain A

Receptor sequence
>7cs1A (length=191) Species: 246196 (Mycolicibacterium smegmatis MC2 155) [Search protein sequence]
IHTARLIHTSDLDQETRDGARRMVIEAFRDDFTDDFTDDDWDHALGGMHA
LISHHGALIAHGAVVQRRLMYRGPDGRGHALRCGYVEAVAVREDRRGDGL
GTAVLDALEQVIRGAYQIGALSASDIARPMYIARGWLSWEGPTSVLTPTE
GIVRTPEDDRSLFVLPVDLPDGLELDTAREITCDWRSGDPW
3D structure
PDB7cs1 Structural and biochemical analyses of an aminoglycoside 2'-N-acetyltransferase from Mycolicibacterium smegmatis.
ChainA
Resolution1.966 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NMY A F42 D54 F55 D59 E106 S141 S143 D144 D177 W210 F28 D35 F36 D40 E87 S122 S124 D125 D158 W191
BS02 COA A F42 V108 A109 V110 R115 G116 G118 G120 T121 M149 F28 V89 A90 V91 R96 G97 G99 G101 T102 M130
BS03 COA A G116 A152 G97 A133
Gene Ontology
Molecular Function
GO:0016746 acyltransferase activity
GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups
Biological Process
GO:0046677 response to antibiotic

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Molecular Function
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Biological Process
External links
PDB RCSB:7cs1, PDBe:7cs1, PDBj:7cs1
PDBsum7cs1
PubMed33299080
UniProtP94968|AAC2_MYCS2 Aminoglycoside 2'-N-acetyltransferase (Gene Name=aac)

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