Structure of PDB 7cs0 Chain A

Receptor sequence
>7cs0A (length=187) Species: 246196 (Mycolicibacterium smegmatis MC2 155) [Search protein sequence]
HTARLIHTSDLDQETRDGARRMVIEAFRTDDFTDDDWDHALGGMHALISH
HGALIAHGAVVQRRLMYRGPDGRGHALRCGYVEAVAVREDRRGDGLGTAV
LDALEQVIRGAYQIGALSASDIARPMYIARGWLSWEGPTSVLTPTEGIVR
TPEDDRSLFVLPVDLPDGLELDTAREITCDWRSGDPW
3D structure
PDB7cs0 Structural and biochemical analyses of an aminoglycoside 2'-N-acetyltransferase from Mycolicibacterium smegmatis.
ChainA
Resolution2.05 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PAR A F42 D54 F55 D59 E106 S141 D177 D208 W210 F27 D31 F32 D36 E83 S118 D154 D185 W187
BS02 COA A F42 V108 V110 R115 G116 G118 G120 T121 S143 A146 F27 V85 V87 R92 G93 G95 G97 T98 S120 A123
BS03 CA A D54 D59 D31 D36
Gene Ontology
Molecular Function
GO:0016746 acyltransferase activity
GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups
Biological Process
GO:0046677 response to antibiotic

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Molecular Function
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Biological Process
External links
PDB RCSB:7cs0, PDBe:7cs0, PDBj:7cs0
PDBsum7cs0
PubMed33299080
UniProtP94968|AAC2_MYCS2 Aminoglycoside 2'-N-acetyltransferase (Gene Name=aac)

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