Structure of PDB 7cq3 Chain A

Receptor sequence
>7cq3A (length=298) Species: 307796 (Saccharomyces cerevisiae YJM789) [Search protein sequence]
QHQFPDFYCCYLLQSINKRQSFYVGSTPNPVRRLRQHNGKLAVGGAYRTK
RDGSRPWEMIMIVRGFPSKIAALQFEHAWQHGYQTHYIAEKDRVVKHKAG
GRTLHHKVALMKLLLKHEFFQRMNLIVEVFNIKAWEVWKQDKFFIERDRF
PINIQINENALEEPKEKTVDVLMDHSDENLKVVEAVYTKVIENERNIFET
FEKKLTTGVVRCEICEKEIDYTSEEQNLKPFVALCNNKDCGCVNHLKCLH
RYFLDDEQLIVGRRNLIPRGGKCPKCDMFCDWTTLVKFSTRMKLAHGK
3D structure
PDB7cq3 Structure specific DNA recognition by the SLX1-SLX4 endonuclease complex.
ChainA
Resolution1.449 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C218 C221 H251 C254 C212 C215 H245 C248
BS02 ZN A C241 C246 C279 C282 C235 C240 C273 C276
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0008821 crossover junction DNA endonuclease activity
GO:0017108 5'-flap endonuclease activity
GO:0046872 metal ion binding
Biological Process
GO:0000724 double-strand break repair via homologous recombination
GO:0006261 DNA-templated DNA replication
GO:0006281 DNA repair
GO:0006310 DNA recombination
GO:1902681 regulation of replication fork arrest at rDNA repeats
GO:2000001 regulation of DNA damage checkpoint
Cellular Component
GO:0000228 nuclear chromosome
GO:0005634 nucleus
GO:0033557 Slx1-Slx4 complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7cq3, PDBe:7cq3, PDBj:7cq3
PDBsum7cq3
PubMed34181713
UniProtP38324|SLX1_YEAST Structure-specific endonuclease subunit SLX1 (Gene Name=SLX1)

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