Structure of PDB 7coj Chain A

Receptor sequence
>7cojA (length=211) Species: 330879 (Aspergillus fumigatus Af293) [Search protein sequence]
SLSDKFSAALAKNKEWAAKCSQEHPELLPTLAVGQHPEILWIGCSDSRCP
ETTILGLLPGDVFTHRNIANVIHPADLSSGAVIEFAVRHLRVKHVVICGH
TKCGGVAAALGNKGLGILDPWLIPLRQLREQHLAELQSLSRDEAVVRLAE
LNVKEGLKALTQKSVVLEAMQERGLQVHGLIYDVGSGFLRQLDAAEPEEA
LKARLTSFKTD
3D structure
PDB7coj Crystal Structure of beta-Carbonic Anhydrase CafA from the Fungal Pathogen Aspergillus fumigatus .
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.2.1.1: carbonic anhydrase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZN A C119 H175 C178 C44 H100 C103
BS02 AZM A C119 D121 H175 G179 G180 C44 D46 H100 G104 G105
BS03 AZM A F138 F160 F63 F85
Gene Ontology
Molecular Function
GO:0004089 carbonate dehydratase activity
GO:0008270 zinc ion binding
GO:0016829 lyase activity
GO:0046872 metal ion binding
Biological Process
GO:0015976 carbon utilization
GO:0034599 cellular response to oxidative stress
GO:0071244 cellular response to carbon dioxide
Cellular Component
GO:0005737 cytoplasm

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7coj, PDBe:7coj, PDBj:7coj
PDBsum7coj
PubMed32975213
UniProtQ4WQ18

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