Structure of PDB 7co1 Chain A

Receptor sequence
>7co1A (length=194) Species: 9606 (Homo sapiens) [Search protein sequence]
PVTYSEPAFWCSIAYYELNQRVGETFHASQPSLTVDGFTDPSNSERFCLG
LLSNVNRNATVEMTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQ
RYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTI
RMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGS
3D structure
PDB7co1 Structural basis for transcriptional coactivator recognition by SMAD2 in TGF-beta signaling.
ChainA
Resolution3.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Q388 V398 W448 Q455 M456 Q124 V134 W184 Q191 M192
Gene Ontology
Biological Process
GO:0006355 regulation of DNA-templated transcription

View graph for
Biological Process
External links
PDB RCSB:7co1, PDBe:7co1, PDBj:7co1
PDBsum7co1
PubMed33323411
UniProtQ15796|SMAD2_HUMAN Mothers against decapentaplegic homolog 2 (Gene Name=SMAD2)

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