Structure of PDB 7cmf Chain A

Receptor sequence
>7cmfA (length=212) Species: 9606 (Homo sapiens) [Search protein sequence]
WVVAPISVPENGKGPFPQRLNQLKSNKDRDTKIFYSITGPGADSPPEGVF
AVEKETGWLLLNKPLDREEIAKYELFGHAVSENGASVEDPMNISIIVTDQ
NDHKPKFTQDTFRGSVLEGVLPGTSVMQVTATDEDDAIYTYNGVVAYSIH
SQEPKDPHDLMFTIHRSTGTISVISSGLDREKVPEYTLTIQATDMDGDGS
TTTAVAVVEILD
3D structure
PDB7cmf Regulation of cadherin dimerization by chemical fragments as a trigger to inhibit cell adhesion
ChainA
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A E11 E69 D100 Q101 D103 D136 E10 E68 D99 Q100 D102 D135
BS02 CA A N102 H104 D134 D136 N143 D195 N101 H103 D133 D135 N142 D194
BS03 CA A E11 N12 D67 E69 D103 E10 N11 D66 E68 D102
BS04 G60 A T99 D100 Y140 T98 D99 Y139
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Biological Process
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
GO:0098609 cell-cell adhesion
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7cmf, PDBe:7cmf, PDBj:7cmf
PDBsum7cmf
PubMed
UniProtP22223|CADH3_HUMAN Cadherin-3 (Gene Name=CDH3)

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