Structure of PDB 7cm1 Chain A

Receptor sequence
>7cm1A (length=387) Species: 2116482 (Wuhan asiatic toad influenza virus) [Search protein sequence]
PKYRMSRPTCRGQKWTVMSNVWTSRWVATGTNARNIRPPTAIFLKKGLRA
VSLAHNTAGPNPLSGTGSDRSEFRDLITWSPSGYPGDESTETICKAWSFF
ACFDGKEDLIGCISGPDNNAVLTIMYGGKPTDLYNSYALDILRTMESQCV
CNNGTCSAMITDGPDIGPSKARMLFIKEGKIEKVVIVDGPGSSMVEECSC
INEDSNEFGCLCRDNTANSRRPFLKCFWDSRTCKADYTCSQTLLDCPRPN
DSIQTCGTSFGSLAGGLKGAYIPLGKGRICATRTVDKIQRKGMELMCTNG
NILLEQDAMKKIGDLVTPTAQTGYSSATTIPRATEECDTICVATELVFSG
AKGTNADLVIHCLLGEARETESVVTAVVDRTTYSSLL
3D structure
PDB7cm1 Lattice-translocation defects in specific crystals of the catalytic head domain of influenza neuraminidase.
ChainA
Resolution2.14 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.1.18: exo-alpha-sialidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A D293 N294 T295 N297 D324 G344 D214 N215 T216 N218 D245 G265
BS02 G39 A D148 R149 R222 E275 E276 R292 R369 Y403 D69 R70 R143 E196 E197 R213 R290 Y324
Gene Ontology
Molecular Function
GO:0004308 exo-alpha-sialidase activity
Biological Process
GO:0005975 carbohydrate metabolic process
Cellular Component
GO:0016020 membrane
GO:0033644 host cell membrane
GO:0055036 virion membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7cm1, PDBe:7cm1, PDBj:7cm1
PDBsum7cm1
PubMed33135677
UniProtA0A2P1GNT2

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