Structure of PDB 7cli Chain A

Receptor sequence
>7cliA (length=292) Species: 9606 (Homo sapiens) [Search protein sequence]
ADGPYLVIVEQPKQRGFRFRYGCEGPSHGGLPGASSEKGRKTYPTVKICN
YEGPAKIEVDLVTHSDPPRAHAHSLVGKQCSELGICAVSVGPKDMTAQFN
NLGVLHVTKKNMMGTMIQKLQRQRLRSGLTEAEQRELEQEAKELKKVMDL
SIVRLRFSAFLRASDGSFSLPLKPVISQPIHDSKSPGASNLKISRMDKTA
GSVRGGDEVYLLCDKVQKDDIEVRFYEDDENGWQAFGDFSPTDVHKQYAI
VFRTPPYHKMKIERPVTVFLQLKRKRGGDVSDSKQFTYYPLV
3D structure
PDB7cli Structures of NF-kappa B p52 homodimer-DNA complexes rationalize binding mechanisms and transcription activation.
ChainA
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A Y55 C57 T142 K143 P223 Y21 C23 T108 K109 P186
BS02 dna A R52 R54 S61 H62 G63 K75 R18 R20 S27 H28 G29 K41
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7cli, PDBe:7cli, PDBj:7cli
PDBsum7cli
PubMed36779700
UniProtQ00653|NFKB2_HUMAN Nuclear factor NF-kappa-B p100 subunit (Gene Name=NFKB2)

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