Structure of PDB 7cl7 Chain A

Receptor sequence
>7cl7A (length=398) Species: 227882 (Streptomyces avermitilis MA-4680 = NBRC 14893) [Search protein sequence]
TRIALDPFVSDLEAESAALRAAGPLAAVELPGGVPVWAVTHHAEAKKLLT
DPRLVKDINVWGAWQRGEIAPDWPLIGLANPGRSMLTVDGADHRRMRTLV
AQALTPRRVEQMRERITKLTEELLDRLTGEVVDLKADFAYPLPMYVVADL
MGIDEARLPRLGELFEKFFSTQTPPAEVIATLTELAGIMAETVAAKRAAP
GDDLTSALILASEDGDHLTDAEIVSTLQLMVAAGHETTISLIVNAVVNLS
THPEQRALVLSGEADWSSVVEETLRYSTPTSHVLIRFATEDVPVGDKVLP
AGDALIVSYGALGRDEAAHGPTAGEFDITRSTENRHISFGHGPHVCPGAA
LSRLEAGVALPALYARFPKLDLAVPAAELRNKPVVTQNDLFELPVRLG
3D structure
PDB7cl7 Substrate-free structure of CYP154C2 in an open conformation
ChainA
Resolution1.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 HEM A H95 R99 L231 A235 G236 T239 V285 R288 Y311 F341 H346 C348 P349 G350 S354 H93 R97 L229 A233 G234 T237 V283 R286 Y309 F339 H344 C346 P347 G348 S352
Gene Ontology
Molecular Function
GO:0004497 monooxygenase activity
GO:0005506 iron ion binding
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0020037 heme binding
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:7cl7, PDBe:7cl7, PDBj:7cl7
PDBsum7cl7
PubMed
UniProtQ82GL5

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