Structure of PDB 7cio Chain A

Receptor sequence
>7cioA (length=109) Species: 9606 (Homo sapiens) [Search protein sequence]
GSEDLPHHDEKTWNVGSSNRNKAENLLRGKRDGTFLVRESSKQGSYAVSV
VVDGEVKHLVINKTATGYGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLN
VTLAYPVYA
3D structure
PDB7cio Molecular interactions of the CTLA-4 cytoplasmic region with the phosphoinositide 3-kinase SH2 domains.
ChainA
Resolution1.1 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A R631 R649 S651 S652 H669 L670 V671 F681 A682 E683 H706 N707 L710 R20 R38 S40 S41 H58 L59 V60 F70 A71 E72 H95 N96 L99
External links
PDB RCSB:7cio, PDBe:7cio, PDBj:7cio
PDBsum7cio
PubMed33386150
UniProtP27986|P85A_HUMAN Phosphatidylinositol 3-kinase regulatory subunit alpha (Gene Name=PIK3R1)

[Back to BioLiP]