Structure of PDB 7ch1 Chain A

Receptor sequence
>7ch1A (length=640) Species: 9606 (Homo sapiens) [Search protein sequence]
PRPRYVVDRAAYSLTLFDDEFEKSAKIKAVVFGLLPVLSWLPKYKIKDYI
IPDLLGGLSGGSIQVPQGMAFALLANLPAVNGLYSSFFPLLTYFFLGGVH
QMVPGTFAVISILVGNICLQLAPESKFQVSYVDTAAMEAERLHVSATLAC
LTAIIQMGLGFMQFGFVAIYLSESFIRGFMTAAGLQILISVLKYIFGLTI
PSYTGPGSIVFTFIDICKNLPHTNIASLIFALISGAFLVLVKELNARYMH
KIRFPIPTEMIVVVVATAISGGCKMPKKYHMQIVGEIQRGFPTPVSPVVS
QWKDMIGTAFSLAIVSYVINLAMGRTLANKHGYDVDSNQEMIALGCSNFF
GSFFKIHVICCALSVTLAVDGAGGKSQVASLCVSLVVMITMLVLGIYLYP
LPKSVLGALIAVNLKNSLKQLTDPYYLWRKSKLDCCIWVVSFLSSFFLSL
PYGVAVGVAFSVLVVVFQTQFRNGYALAQVMDTDIYVNPKTYNRAQDIQG
IKIITYCSPLYFANSEIFRQKVIAKTGMDPQKVLLAKQKLASVPPFVTFH
TLILDMSGVSFVDLMGIKALAKLSSTYGKIGVKVFLVNIHAQVYNDISHG
GVFEDGSLECKHVFPSIHDAVLFAQANADLEQEMFGSMFH
3D structure
PDB7ch1 Structural insights into the gating mechanism of human SLC26A9 mediated by its C-terminal sequence.
ChainA
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 CL A N97 R169 N76 R141
BS02 CL A T127 F128 I131 H385 V386 T106 F107 I110 H357 V358
BS03 NA A Q85 G89 S107 G126 T127 Q64 G68 S86 G105 T106
Gene Ontology
Molecular Function
GO:0005254 chloride channel activity
GO:0005452 solute:inorganic anion antiporter activity
GO:0015106 bicarbonate transmembrane transporter activity
GO:0015108 chloride transmembrane transporter activity
GO:0015116 sulfate transmembrane transporter activity
GO:0019531 oxalate transmembrane transporter activity
GO:0051117 ATPase binding
Biological Process
GO:0006811 monoatomic ion transport
GO:0006820 monoatomic anion transport
GO:0006821 chloride transport
GO:0010628 positive regulation of gene expression
GO:0015701 bicarbonate transport
GO:0019532 oxalate transport
GO:0055085 transmembrane transport
GO:1902358 sulfate transmembrane transport
GO:1902476 chloride transmembrane transport
Cellular Component
GO:0000139 Golgi membrane
GO:0005789 endoplasmic reticulum membrane
GO:0005886 plasma membrane
GO:0009986 cell surface
GO:0010008 endosome membrane
GO:0012505 endomembrane system
GO:0016020 membrane
GO:0016324 apical plasma membrane
GO:0070062 extracellular exosome

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7ch1, PDBe:7ch1, PDBj:7ch1
PDBsum7ch1
PubMed32818062
UniProtQ7LBE3|S26A9_HUMAN Solute carrier family 26 member 9 (Gene Name=SLC26A9)

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