Structure of PDB 7cer Chain A

Receptor sequence
>7cerA (length=414) Species: 224308 (Bacillus subtilis subsp. subtilis str. 168) [Search protein sequence]
GHMNITDIREQFPILHQQVNGHDLVYLDSAATSQKPRAVIETLDKYYNQY
NSNVHRGVHTLGTRATDGYEGAREKVRKFINAKSMAEIIFTKGTTTSLNM
VALSYARANLKPGDEVVITYMEAHANIIPWQQAVKATGATLKYIPLQEDG
TISLEDVRETVTSNTKIVAVSHVSNVLGTVNPIKEMAKIAHDNGAVIVVD
GAQSTPHMKIDVQDLDCDFFALSSHKMCGPTGVGVLYGKKALLENMEPAE
FGGEMIDFVGLYESTWKELPWKFEAGTPIIAGAIGLGAAIDFLEEIGLDE
ISRHEHKLAAYALERFRQLDGVTVYGPEERAGLVTFNLDDVHPHDVATVL
DAEGIAVRAGHHCAQPLMKWLDVTATARASFYLYNTEEEIDKLVEALQKT
KEYFTNVFVDLEHH
3D structure
PDB7cer Cycloserine enantiomers inhibit PLP-dependent cysteine desulfurase SufS via distinct mechanisms.
ChainA
Resolution2.3 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.8.1.7: cysteine desulfurase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 DCS A A28 T92 T93 N173 D198 A200 S221 H223 K224 R356 R376 A30 T94 T95 N175 D200 A202 S223 H225 K226 R358 R378
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0005515 protein binding
GO:0016740 transferase activity
GO:0030170 pyridoxal phosphate binding
GO:0031071 cysteine desulfurase activity
Biological Process
GO:0006534 cysteine metabolic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:7cer, PDBe:7cer, PDBj:7cer
PDBsum7cer
PubMed35395703
UniProtO32164|SUFS_BACSU Cysteine desulfurase SufS (Gene Name=sufS)

[Back to BioLiP]