Structure of PDB 7cec Chain A

Receptor sequence
>7cecA (length=553) Species: 9606 (Homo sapiens) [Search protein sequence]
FNLDTREDNVIRKYGDPGSLFGFSLAMHWQLQPEDKRLLLVGAPRAEALP
LQRANRTGGLYSCDITARGPCTRIEFDNDADPTSESKEDQWMGVTVQSQG
PGGKVVTCAHRYEKRQHVNTKQESRDIFGRCYVLSQNLRIEDDMDGGDWS
FCDGRLRGHEKFGSCQQGVAATFTKDFHYIVFGAPGTYNWKGIVRVEQDG
PYEVGPVPANSYLGFSLDSGKGIVSKDEITFVSGAPRANHSGAVVLLKRD
MKSAHLLPEHIFDGEGLASSFGYDVAVVDLNKDGWQDIVIGAPQYFDRDG
EVGGAVYVYMNQQGRWNNVKPIRLNGTKDSMFGIAVKNIGDINQDGYPDI
AVGAPYDDLGKVFIYHGSANGINTKPTQVLKGISPYFGYSIAGNMDLDRN
SYPDVAVGSLSDSVTIFRSRPVINIQKTITVTPNRIDLRQKTACGAPSGI
CLQVKSCFEYTANPAGYNPSISIVGTLEAEKESSRVQFRKYTQELTLKRQ
KQKVCMEETLWLQDNLRPIPITASVEIQEPLPEVLPILNSDEPKTAHIDV
HFL
3D structure
PDB7cec Structural mechanism of laminin recognition by integrin.
ChainA
Resolution3.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A D301 N303 D305 W307 D309 N333 D279 N281 D283 W285 D287 N311
BS02 CA A D363 N365 D367 Y369 D371 D341 N343 D345 Y347 D349
BS03 CA A D418 D420 N422 Y424 D426 S441 D396 D398 N400 Y402 D404 S419
Gene Ontology
Cellular Component
GO:0008305 integrin complex

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Biological Process
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Cellular Component
External links
PDB RCSB:7cec, PDBe:7cec, PDBj:7cec
PDBsum7cec
PubMed34188035
UniProtP23229|ITA6_HUMAN Integrin alpha-6 (Gene Name=ITGA6)

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