Structure of PDB 7cba Chain A

Receptor sequence
>7cbaA (length=768) Species: 8656 (Naja atra) [Search protein sequence]
QDICVLPTQSWSCNKLRCGEKRMANVLCSCSEDCLTKKDCCTDYKSICKR
ETSWLKDQCASSQCPEGFDQSPLILFSMDGFRAEYLETWDTLMPNINKLK
TCGTHAKYMRAVYPTKTFVNHYTIVTGLYAETHGIIDNNMYDVKLNQNFS
LSGSNMRNAAWWGGQPIWHTASYQGLKAATYFWPGSEVKINGSYPTIYKV
YNKSTPFEARVMEVLKWLDLPKAKRPDFSTLYIEEPDTTGHKFGPVSGQV
IKSLQMADRTLGMLMEGLKQRNLHNCVNLILLADHGMEAISCNRLEYMTD
YFNTVDFFMYEGAAPRIRSKNVPKDFYTFDSEAIVKKLTCRKPKQHFKAY
LAKDLPKRLHFANNIRIDKVNLMVDRQWLAVRNKKCSGGTHGYDNEFKSM
EAIFLAHGPGFKEKTEVTSFENIEVYNLMCDLLKLKPAPNNGTHGSLNHL
LKNPFYNPSPAKEQSPPLYCLFGPVPSPDVSGCKCSSITDLEAVNQRLNL
IDQAKMQSEADNLPYGRPHVLQHSKYCLLHQTKYISAYSQDILMPLWNSY
TISKSLDCLRLDVRIPTVQSQTCSNYQPDLAITPGFLYPPDFSSSGPEQY
DALITSNIVPMYKEFARLWNYFHSTLLPKYATERNGLNVISGPIFDYNYD
GHFDPYDTIDQYVNNTKIPIPTHYFVVLTSCENSTKTPLNCPPGSLKVLS
FILPHRPDNSESCADKSPDNLWVEERMQTHTARVRDVELLTGLDFYSALK
QPLSETLRLKTFLPIFIN
3D structure
PDB7cba Crystal structure of snake venom phosphodiesterase (PDE) from Taiwan cobra (Naja atra atra) in complex with isorhamnetin and citrate
ChainA
Resolution2.901 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A D305 H309 H462 D237 H241 H391
BS02 ZN A D147 T185 D352 H353 D79 T117 D284 H285
BS03 CA A D728 N730 D732 H734 F735 D736 D646 N648 D650 H652 F653 D654
BS04 IRH A F186 W251 P252 Y269 K271 Y300 E302 D305 T306 F118 W183 P184 Y201 K203 Y232 E234 D237 T238
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0016787 hydrolase activity
GO:0043262 ADP phosphatase activity
GO:0046872 metal ion binding
GO:0047429 nucleoside triphosphate diphosphatase activity
GO:0090729 toxin activity
Biological Process
GO:0009143 nucleoside triphosphate catabolic process
GO:0035821 modulation of process of another organism
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7cba, PDBe:7cba, PDBj:7cba
PDBsum7cba
PubMed
UniProtA0A2D0TC04|PDE_NAJAT Venom phosphodiesterase

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