Structure of PDB 7c7c Chain A

Receptor sequence
>7c7cA (length=429) Species: 9606 (Homo sapiens) [Search protein sequence]
PLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISN
ASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELV
SNLFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGV
RTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQA
IWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPD
MKPSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLQESALIRKLR
DVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIA
KLLRYESSALPSGQLTSLSEYASRMRNIYYLCAPNRHLAEHSPYYEAMTE
VLFCFEQFDELTLLHLREFDKKKLISVET
3D structure
PDB7c7c Design and Synthesis of TRAP1 Selective Inhibitors: H-Bonding with Asn171 Residue in TRAP1 Increases Paralog Selectivity.
ChainA
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FK0 A A123 M163 F201 F205 W231 A54 M94 F104 F108 W134
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:0051082 unfolded protein binding
GO:0140662 ATP-dependent protein folding chaperone
Biological Process
GO:0006457 protein folding

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Molecular Function
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Biological Process
External links
PDB RCSB:7c7c, PDBe:7c7c, PDBj:7c7c
PDBsum7c7c
PubMed34267888
UniProtQ12931|TRAP1_HUMAN Heat shock protein 75 kDa, mitochondrial (Gene Name=TRAP1)

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