Structure of PDB 7c6a Chain A

Receptor sequence
>7c6aA (length=373) Species: 562,9606 [Search protein sequence]
CSQKPSDKHLDAIPILYYIIFVIGFLVNIVVVTLFCCQKGPKKVSSIYIF
NLAVADLLVLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIWF
ITCMSVDRYQSVIYPFNPWQASYIVPLVWCMACLSSLPTFYFRDVRTIEY
LGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLL
KTNADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDAQKAMKDF
RHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNAYIQKYLKNRIT
RDQVLKMAAAVVLAFIICWLPFHVLTFLDALAWMGVINSCEVIAVIDLAL
PFAILLGFTNSCVNPFLYCFVGN
3D structure
PDB7c6a The discovery of a new antibody for BRIL-fused GPCR structure determination.
ChainA
Resolution3.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A S36 Y103 Y104 Y108 R182 I187 E188 I196 M197 Y204 K215 D279 W283 D297 L300 I304 S2 Y69 Y70 Y74 R143 I148 E149 I157 M158 Y165 K176 D329 W333 D347 L350 I354
Gene Ontology
Molecular Function
GO:0004930 G protein-coupled receptor activity
GO:0004945 angiotensin type II receptor activity
GO:0005506 iron ion binding
GO:0009055 electron transfer activity
GO:0020037 heme binding
GO:0046872 metal ion binding
Biological Process
GO:0006954 inflammatory response
GO:0007186 G protein-coupled receptor signaling pathway
GO:0022900 electron transport chain
GO:0042981 regulation of apoptotic process
GO:0097746 blood vessel diameter maintenance
Cellular Component
GO:0016020 membrane
GO:0042597 periplasmic space

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Biological Process
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Cellular Component
External links
PDB RCSB:7c6a, PDBe:7c6a, PDBj:7c6a
PDBsum7c6a
PubMed32669569
UniProtP0ABE7|C562_ECOLX Soluble cytochrome b562 (Gene Name=cybC);
P50052|AGTR2_HUMAN Type-2 angiotensin II receptor (Gene Name=AGTR2)

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