Structure of PDB 7c0i Chain A

Receptor sequence

>7c0iA (length=61) Species: 9606,10254

RSNAEIVCEAIKTIGIGATAAQLTRQLNMEKKEINRVLYSLAKKGKVYSS
DDIPPRWFMTT

3D structure

• PDB: 7c0i Dual conformational recognition by Z-DNA binding protein is important for the B-Z transition process.
• Chain: A
• Resolution: 2.4 Å

Enzymatic activity

• Enzyme Commision number:
  3.5.4.37: double-stranded RNA adenine deaminase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	dna	A	K1169 K1170 N1173 R1174 Y1177 I62 P1192 P1193	K31 K32 N35 R36 Y39 I53 P54 P55

Gene Ontology

Molecular Function

• GO:0003723 RNA binding
• GO:0003726 double-stranded RNA adenosine deaminase activity

External links

• PDB: RCSB:7c0i, PDBe:7c0i, PDBj:7c0i
• PDBsum: 7c0i
• PubMed: 33245772
• UniProt: P21605;
  P55265|DSRAD_HUMAN Double-stranded RNA-specific adenosine deaminase (Gene Name=ADAR)