Structure of PDB 7by1 Chain A

Receptor sequence
>7by1A (length=287) Species: 10090 (Mus musculus) [Search protein sequence]
SQRKAQVRGLPRAKKLEKLGVFSACKANETCKCNGWKNPKPPPAANLSEL
CRSCEHPLADHVSHLENVSEDEINRLLGMVVDVENLFMSVHKEEDTDTKQ
VYFYLFKLLRKCILQMTRPVVEGSLGSPPFEKPNIEQGVLNFVQYKFSHL
APRERQTMFELSKMFLLCLNYWKLETPAQFRQRSQSEDVATYKVNYTRWL
CYCHVPQSCDSLPRYETTHVFGRSLLRSIFTVTRRQLLEKFRVEKDKLVP
EKRTLILTHFPKFLSMLEEEIYGANSPIWESGFTMPP
3D structure
PDB7by1 Crystal structure of GCN5 PCAF N-terminal domain reveals atypical ubiquitin ligase structure.
ChainA
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.-
2.3.1.48: histone acetyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C107 C113 C145 H147 C25 C31 C54 H56
BS02 ZN A C115 C142 C145 H152 C33 C51 C54 H61
Gene Ontology
Molecular Function
GO:0004402 histone acetyltransferase activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7by1, PDBe:7by1, PDBj:7by1
PDBsum7by1
PubMed32820047
UniProtQ9JHD2|KAT2A_MOUSE Histone acetyltransferase KAT2A (Gene Name=Kat2a)

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