Structure of PDB 7bu2 Chain A

Receptor sequence
>7bu2A (length=337) Species: 562 (Escherichia coli) [Search protein sequence]
SMIKSYAAKEAGGELEVYEYDPGELRPQDVEVQVDYCGICHSDLSMIDNE
WGFSQYPLVAGHEVIGRVVALGSAAQDKGLQVGQRVGIGWTARSCGHCDA
CISGNQINCEQGAVPTIMNRGGFAEKLRADWQWVIPLPENIDIESAGPLL
CGGITVFKPLLMHHITATSRVGVIGIGGLGHIAIKLLHAMGCEVTAFSSN
PAKEQEVLAMGADKVVNSRDPQALKALAGQFDLIINTVNVSLDWQPYFEA
LTYGGNFHTVGAVLTPLSVPAFTLIAGDRSVSGSATGTPYELRKLMRFAA
RSKVAPTTELFPMSKINDAIQHVRDGKARYRVVLKAD
3D structure
PDB7bu2 Structural Basis for Broad Substrate Selectivity of Alcohol Dehydrogenase YjgB from Escherichia coli .
ChainA
Resolution1.553 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.1.1.2: alcohol dehydrogenase (NADP(+)).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C41 H63 E64 C152 C40 H62 E63 C151
BS02 ZN A C96 C99 C102 C110 C95 C98 C101 C109
Gene Ontology
Molecular Function
GO:0008106 alcohol dehydrogenase (NADP+) activity
GO:0008270 zinc ion binding
GO:0016491 oxidoreductase activity
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0042803 protein homodimerization activity
GO:0046872 metal ion binding
Biological Process
GO:0006631 fatty acid metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:7bu2, PDBe:7bu2, PDBj:7bu2
PDBsum7bu2
PubMed32455802
UniProtP27250|AHR_ECOLI Aldehyde reductase Ahr (Gene Name=ahr)

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