Structure of PDB 7brg Chain A

Receptor sequence
>7brgA (length=426) Species: 10116 (Rattus norvegicus) [Search protein sequence]
SDLTVAVVLPLTNTSYPWSWARVGPAVELALARVKARPDLLPGWTVRMVL
GSSENAAGVCSDTAAPLAAVDLKWEHSPAVFLGPGCVYSAAPVGRFTAHW
RVPLLTAGAPALGIGVKDEYALTTRTGPSHVKLGDFVTALHRRLGWEHQA
LVLYADRLGDDRPCFFIVEGLYMRVRERLNITVNHQEFVEGDPDHYPKLL
RAVRRKGRVIYICSSPDAFRNLMLLALNAGLTGEDYVFFHLDVFGQSLKS
AQGLVPQKPWERGDGQDRSARQAFQAAKIITYKEPDNPEYLEFLKQLKLL
ADKKFNFTVEDGLKNIIPASFHDGLLLYVQAVTETLAQGGTVTDGENITQ
RMWNRSFQGVTGYLKIDRNGDRDTDFSLWDMDPETGAFRVVLNYNGTSQE
LMAVSEHKLYWPLGYPPPDVPKCGFD
3D structure
PDB7brg Structural insight into hormone-recognition and transmembrane signaling by the atrial natriuretic peptide receptor
ChainA
Resolution2.45 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.6.1.2: guanylate cyclase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A D62 Y88 R95 G113 F165 V168 E169 M173 R176 H185 E187 D62 Y88 R95 G113 F165 V168 E169 M173 R176 H185 E187
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:7brg, PDBe:7brg, PDBj:7brg
PDBsum7brg
PubMed
UniProtP18910|ANPRA_RAT Atrial natriuretic peptide receptor 1 (Gene Name=Npr1)

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