Structure of PDB 7bre Chain A

Receptor sequence
>7breA (length=179) Species: 9606 (Homo sapiens) [Search protein sequence]
SRVLLALHDRAPQLKISDDRLTVVGEKGYSMVRASHGVRKGAWYFEITVD
EMPPDTAARLGWSQPLGNLQAPLGYDKFSYSWRSKKGTKFHQSIGKHYSS
GYGQGDVLGFYINLPEDRGSSEIIFYKNGVNQGVAYKDIFEGVYFPAISL
YKSCTVSINFGPCFKYPPKDLTYRPMSDM
3D structure
PDB7bre Crystal Structure of MLL2 Complex Guides the Identification of a Methylation Site on P53 Catalyzed by KMT2 Family Methyltransferases.
ChainA
Resolution2.803 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A G312 Y313 R343 P356 R367 S377 Y475 G28 Y29 R59 P72 R83 S93 Y151
Gene Ontology
Cellular Component
GO:0048188 Set1C/COMPASS complex

View graph for
Cellular Component
External links
PDB RCSB:7bre, PDBe:7bre, PDBj:7bre
PDBsum7bre
PubMed32697937
UniProtQ9UBL3|ASH2L_HUMAN Set1/Ash2 histone methyltransferase complex subunit ASH2 (Gene Name=ASH2L)

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