Structure of PDB 7bq1 Chain A

Receptor sequence
>7bq1A (length=261) Species: 9606 (Homo sapiens) [Search protein sequence]
DLKSLAKRIYEAYLKNFNMNKVKARVILSGNNPPFVIHDMETLCMAEKTL
VAKLVANNKEAEVRIFHCCQCTSVETVTELTEFAKAIPGFANLDLNDQVT
LLKYGVYEAIFAMLSSVMNKDGMLVAYGNGFITREFLKSLRKPFCDIMEP
KFDFAMKFNALELDDSDISLFVAAIICCGDRPGLLNVGHIEKMQEGIVHV
LRLHLQSNHPDDIFLFPKLLQKMADLRQLVTEHAQLVQIIKKTESDAALH
PLLQEIYRDMY
3D structure
PDB7bq1 PPAR alpha Ligand-Binding Domain Structures with Endogenous Fatty Acids and Fibrates.
ChainA
Resolution1.521 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A T288 K292 Q305 V306 K310 L459 E462 T81 K85 Q98 V99 K103 L252 E255
BS02 PLM A C276 S280 Y314 M355 H440 C69 S73 Y107 M148 H233
BS03 GOL A K222 R226 S323 M325 N366 K21 R25 S116 M118 N159
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7bq1, PDBe:7bq1, PDBj:7bq1
PDBsum7bq1
PubMed33205029
UniProtQ07869|PPARA_HUMAN Peroxisome proliferator-activated receptor alpha (Gene Name=PPARA)

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