Structure of PDB 7boc Chain A

Receptor sequence
>7bocA (length=211) Species: 9606 (Homo sapiens) [Search protein sequence]
LCMPVFHPRFKDWNTLIVGKLSPWIRPDSKVEKIRRNSEAAMLQELNFGA
YLGLPAFLLPLNQEDNTNLARVLTNHIHTGHHSSMFWMRVPLVAPEDLRY
SGEEKTWMWWHNFRTLCDYSKRIAVALEIGADLPSNHVIDRWLGEPIKAA
ILPTSIFLTNKKGFPVLSKMHQRLIFRLLKLEVQFIITGTNHHSEKEFCS
YLQYLEYLSQN
3D structure
PDB7boc Biochemical Investigation of the Interaction of pICln, RioK1 and COPR5 with the PRMT5-MEP50 Complex.
ChainA
Resolution2.55 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.320: type II protein arginine methyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A L237 N239 K240 K241 F243 K248 Q282 Y283 Y286 L158 N160 K161 K162 F164 K169 Q203 Y204 Y207
Gene Ontology
Molecular Function
GO:0016274 protein-arginine N-methyltransferase activity
Biological Process
GO:0018216 peptidyl-arginine methylation

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Molecular Function
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Biological Process
External links
PDB RCSB:7boc, PDBe:7boc, PDBj:7boc
PDBsum7boc
PubMed33624332
UniProtO14744|ANM5_HUMAN Protein arginine N-methyltransferase 5 (Gene Name=PRMT5)

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