Structure of PDB 7bn8 Chain A

Receptor sequence
>7bn8A (length=348) Species: 9606 (Homo sapiens) [Search protein sequence]
DLRLHLLLNTSVTCNDGSPAGYYLKESRGSRRWLLFLEGGWYCFNRENCD
SRYDTMRRLMSSRDWPRTRTGTGILSSQPEENPYWWNANMVFIPYCSSDV
WSGASSKSEKNEYAFMGALIIQEVVRELLGRGLSGAKVLLLAGSSAGGTG
VLLNVDRVAEQLEKLGYPAIQVRGLADSGWFLDNKQYRHTDCCAPTEAIR
RGIRYWNGVVPERCRRQFQEGEEWNCFFGYKVYPTLRSPVFVVQWLFDEA
QLTVDNVHQPVQEGLRLYIQNLGRELRHTLKDVPASFAPACLSHEIIIRS
HWTDVQVKGTSLPRALHCWDRSLHPLKGCPVHLVDSCPWPHCNPSCPT
3D structure
PDB7bn8 Notum Inhibitor
ChainA
Resolution1.78 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.1.98: [Wnt protein] O-palmitoleoyl-L-serine hydrolase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 U4T A G127 W128 S232 A233 F268 F319 G40 W41 S145 A146 F181 F227
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity

View graph for
Molecular Function
External links
PDB RCSB:7bn8, PDBe:7bn8, PDBj:7bn8
PDBsum7bn8
PubMed
UniProtQ6P988|NOTUM_HUMAN Palmitoleoyl-protein carboxylesterase NOTUM (Gene Name=NOTUM)

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