Structure of PDB 7bke Chain A

Receptor sequence

>7bkeA (length=447) Species: 323259 (Methanospirillum hungatei JF-1)

KSVPVEKTAMVVGGGVAGMQAALDLASAGIKTYLIERTPTIGGRMSQLDK
TFPTLDCSQCILTPKMVDVGRHPNIEMMTYTEVEKVEGYIGNFDVTLRKK
ARGVLTPTEATAKGIVGGGCNGCGDCSAVCPVIKPNPFEMGMAPRKAIYI
YHAQVMPLIYTVDFDSCVKCGLCVEACGDKKAIDLEMQDEFITVKVGTAV
LATGYELFPIENKREWGYKQFDNVINALEFERLICASGPTGGHLVRPSDG
KTPMKVGFVLCAGSRDNTGIGKPYCSRFCCMYSLKHAHQIMEKIPGAVAY
LFYMDIRSFGKMYEEFYYRIQHEGAKFIRGRVANVLEDKETKNLHVFTED
TLLGRPVDVEVDLLVLAAAVQPNEGANELRKKFGVSASQDGWMLEAHPKL
NPCGTTTAGVFLAGVCQGPKDIPDTVAQAEGAASAASIPIHMGEVEL

3D structure

• PDB: 7bke Three-megadalton complex of methanogenic electron-bifurcating and CO 2 -fixing enzymes.
• Chain: A
• Resolution: 2.8 Å

Enzymatic activity

• Enzyme Commision number: 1.8.-.-

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	SF4	A	C402 S405 R406 C416 S417 R418 C420 C421	C261 S264 R265 C275 S276 R277 C279 C280
BS02	FAD	A	V153 G156 V157 A158 E177 R178 G184 R185 L189 T192 F193 T344 G345 Y346 A368 F419 Y423 K426 V556 K561 D562 I563	V12 G15 V16 A17 E36 R37 G43 R44 L48 T51 F52 T203 G204 Y205 A227 F278 Y282 K285 V415 K420 D421 I422
BS03	SF4	A	C261 N262 G263 C264 G265 C267 Y301 C318 K321 I324	C120 N121 G122 C123 G124 C126 Y160 C177 K180 I183
BS04	SF4	A	C271 P272 A288 I289 C308 V309 K310 C311 G312 C314 L326	C130 P131 A147 I148 C167 V168 K169 C170 G171 C173 L185

Gene Ontology

Molecular Function

• GO:0016491 oxidoreductase activity
• GO:0046872 metal ion binding
• GO:0051539 4 iron, 4 sulfur cluster binding

External links

• PDB: RCSB:7bke, PDBe:7bke, PDBj:7bke
• PDBsum: 7bke
• PubMed: 34516836
• UniProt: Q2FKZ1