Structure of PDB 7bil Chain A

Receptor sequence

>7bilA (length=436) Species: 751945 (Thermus oshimai JL-2) [Search protein sequence]

GLSSEQQRAFLAVTQTPHPAHLITGPAGTGKTTLLYALQEFYKGRAVTLA
PTGTAALQARGQTVHSFFRFPARLLRYRHPEDIRPPGPHSPLRKAIEQME
VLILDEVGMVRVDLLEAMDWALRKTRKRLEEPFGGVKVLLLGDTRQLEPV
VPGGEEALYIARTWGGPFFFQAHVWEEVALRVHRLWESQRQREDPLFAEL
LKRLRQGDPQALETLNRAAVRPDGGEEPGTLILTPRRKEADALNLKRLEA
LPGKPLEYQAQVKGEFAETDFPTEAALTLKKGAQVILLRNDPLGEYFNGD
LGWVEDLEAEALAVRLKRNGRRVVIRPFVWEKIVYTYDSEREEIKPQVVG
TFRQVPVRLAWALTVHKAQGLTLDKVHLELGRGLFAHGQLYVALTRVRRL
QDLSLSRPIAPTELLWRPEVEVFETRIQEGIWQKSH

3D structure

PDB

7bil Structural and functional studies of SF1B Pif1 from Thermus oshimai reveal dimerization-induced helicase inhibition.

Chain

Resolution

2.21 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	dna	A	P117 T118 G119 T129 H131 A138 V216 P218 R302 R303 R355 N356 P358 N364 R392 F394 V395 W396 E397 H432 K433 R448 F451	P51 T52 G53 T63 H65 A72 V150 P152 R236 R237 R289 N290 P292 N298 R326 F328 V329 W330 E331 H366 K367 R382 F385
BS02	ADP	A	Q72 G94 G96 K97 T98 T99 Q255 R256	Q6 G28 G30 K31 T32 T33 Q189 R190
BS03	ALF	A	A93 G94 K97 E172 Q212 R256 G436 R462	A27 G28 K31 E106 Q146 R190 G370 R396

Gene Ontology

	Molecular Function
GO:0000166	nucleotide binding
GO:0003678	DNA helicase activity
GO:0004386	helicase activity
GO:0016887	ATP hydrolysis activity
GO:0046872	metal ion binding

	Biological Process
GO:0000723	telomere maintenance
GO:0006281	DNA repair
GO:0032508	DNA duplex unwinding

View graph for
Molecular Function

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Biological Process

External links

PDB	RCSB:7bil, PDBe:7bil, PDBj:7bil
PDBsum	7bil
PubMed	33784404
UniProt	K7RJ88

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