Structure of PDB 7bh8 Chain A

Receptor sequence
>7bh8A (length=276) Species: 9606 (Homo sapiens) [Search protein sequence]
GSHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDNDAASPRMVPRAP
WMEQEGSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMHG
CELGPDGRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQKSNDA
SEAEHQRAYLEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEAT
LRCWALGFYPAEITLTWQQDGEGHTQDTELVETRPAGDGTFQKWAAVVVP
SGEEQRYTCHVQHEGLPEPVTLRWKP
3D structure
PDB7bh8 Mouse and human antibodies bind HLA-E-leader peptide complexes and enhance NK cell cytotoxicity.
ChainA
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A Y7 H9 E63 A67 I73 N77 Y84 W97 F116 W133 S143 E152 H155 Q156 Y159 W167 Y171 Y7 H9 E63 A67 I73 N77 Y84 W97 F116 W133 S143 E152 H155 Q156 Y159 W167 Y171
External links
PDB RCSB:7bh8, PDBe:7bh8, PDBj:7bh8
PDBsum7bh8
PubMed35347236
UniProtP13747|HLAE_HUMAN HLA class I histocompatibility antigen, alpha chain E (Gene Name=HLA-E)

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