Structure of PDB 7bgm Chain A

Receptor sequence
>7bgmA (length=213) Species: 3880 (Medicago truncatula) [Search protein sequence]
SNAVDSLLDSVKWDNKGLAVAIAQNVDTGAILMQGFANREAVATTISSRK
ATFYSRSRSSLWTKGETSNNFINVHDVFLDCDRDSIIYLGKPDGPTCHTG
AETCYYTPVFDLLKEEEVEGNKLALTSLYALESTISQRKAEVVSWTKRLL
LNDKLLCSKIREEANELCETLENNEDKSRTASEMADVLYHAMVLLALKDV
KVEEVLQVLRQRF
3D structure
PDB7bgm Structural and mechanistic insights into the bifunctional HISN2 enzyme catalyzing the second and third steps of histidine biosynthesis in plants.
ChainA
Resolution1.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.-.-.-
3.5.4.19: phosphoribosyl-AMP cyclohydrolase.
3.6.1.31: phosphoribosyl-ATP diphosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C142 C149 C97 C104
BS02 ZN A D125 D127 D129 D80 D82 D84
BS03 ZN A E214 E234 D237 E163 E183 D186
Gene Ontology
Molecular Function
GO:0004635 phosphoribosyl-AMP cyclohydrolase activity
GO:0004636 phosphoribosyl-ATP diphosphatase activity
Biological Process
GO:0000105 L-histidine biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:7bgm, PDBe:7bgm, PDBj:7bgm
PDBsum7bgm
PubMed33958623
UniProtA0A072U2X9

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