Structure of PDB 7bdc Chain A

Receptor sequence
>7bdcA (length=341) Species: 9606 (Homo sapiens) [Search protein sequence]
DLRLHLLLNTSVTCNDGSPAGYYLKESRGSRRWLLFLEGGWYCFNRENCD
SRYDTMRRLMSSRDWPRTRTGTGILSSQPEENPYWWNANMVFIPYCSSDV
WSGASSKSEKNEYAFMGALIIQEVVRELLGRGLSGAKVLLLAGSSAGGTG
VLLNVDRVAEQLEKLGYPAIQVRGLADSGWFLDNKQYRHTEAIRRGIRYW
NGVVPERCRRQFQEGEEWNCFFGYKVYPTLRSPVFVVQWLFDEAQLTVDN
VHPVQEGLRLYIQNLGRELRHTLKDVPASFAPACLSHEIIIRSHWTDVQV
KGTSLPRALHCWDRSLHPLKGCPVHLVDSCPWPHCNPSCPT
3D structure
PDB7bdc Structural Analysis and Development of Notum Fragment Screening Hits.
ChainA
Resolution1.32 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.1.98: [Wnt protein] O-palmitoleoyl-L-serine hydrolase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 WNA A W128 Y129 A233 T236 F268 V346 W41 Y42 A146 T149 F181 V248
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity

View graph for
Molecular Function
External links
PDB RCSB:7bdc, PDBe:7bdc, PDBj:7bdc
PDBsum7bdc
PubMed35731924
UniProtQ6P988|NOTUM_HUMAN Palmitoleoyl-protein carboxylesterase NOTUM (Gene Name=NOTUM)

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