Structure of PDB 7bai Chain A

Receptor sequence
>7baiA (length=120) Species: 9606 (Homo sapiens) [Search protein sequence]
ENKKLLCRKCKALACYTADVRVIEECHYTVLGDAFKECFVSRPHPKPKQF
SSFEKRAKIFCARQNCSHDWGIHVKYKTFEIPVIKIESFVVEDIATGVQT
LYSKWKDFHFEKIPFDPAEM
3D structure
PDB7bai A conserved isoleucine in the RNA sensor RIG-I controls immune tolerance to mitochondrial RNA
ChainA
Resolution3.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.13: RNA helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna A C829 H830 F853 K858 G874 K888 W908 C26 H27 F50 K55 G71 K85 W105
BS02 rna A F853 S854 F50 S51
BS03 ZN A C810 C864 C869 C7 C61 C66
External links
PDB RCSB:7bai, PDBe:7bai, PDBj:7bai
PDBsum7bai
PubMed
UniProtO95786|RIGI_HUMAN Antiviral innate immune response receptor RIG-I (Gene Name=RIGI)

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