Structure of PDB 7bah Chain A

Receptor sequence
>7bahA (length=121) Species: 9606 (Homo sapiens) [Search protein sequence]
KENKKLLCRKCKALACYTADVRVIEECHYTVLGDAFKECFVSRPHPKPKQ
FSSFEKRAKIFCARQNCSHDWGIHVKYKTFEIPVIKIESFVVEDIATGVQ
TLYSKWKDFHFEKIPFDPAEM
3D structure
PDB7bah A conserved isoleucine in the RNA sensor RIG-I controls immune tolerance to mitochondrial RNA
ChainA
Resolution1.89 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.13: RNA helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna A C829 H830 F853 K858 I875 K888 C27 H28 F51 K56 I73 K86
BS02 rna A F853 S854 F51 S52
BS03 ZN A C810 C813 C864 C869 C8 C11 C62 C67
External links
PDB RCSB:7bah, PDBe:7bah, PDBj:7bah
PDBsum7bah
PubMed
UniProtO95786|RIGI_HUMAN Antiviral innate immune response receptor RIG-I (Gene Name=RIGI)

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