Structure of PDB 7bag Chain A

Receptor sequence
>7bagA (length=640) Species: 9606 (Homo sapiens) [Search protein sequence]
SPMYSIITPNILRLESEETMVLEAHDAQGDVPVTVTVHDFPGKKLVLSSE
KTVLTPATNHMGNVTFTIPANREFKKGRNKFVTVQATFGTQVVEKVVLVS
LQSGYLFIQTDKTIYTPGSTVLYRIFTVNHKLLPVGRTVMVNIENPEGIP
VKQDSLSSQNQLGVLPLSWDIPELVNMGQWKIRAYYENSPQQVFSTEFEV
KEYVLPSFEVIVEPTEKFYYIYNEKGLEVTITARFLYGKKVEGTAFVIFG
IQDGEQRISLPESLKRIPIEDGSGEVVLSRKVLLDGVQNPRAEDLVGKSL
YVSATVILHSGSDMVQAERSGIPIVTSPYQIHFTKTPKYFKPGMPFDLMV
FVTNPDGSPAYRVPVAVQGEDTVQSLTQGDGVAKLSINTHPSQKPLSITV
RTKKQELSEAEQATRTMQALPYSTVGNSNNYLHLSVLRTELRPGETLNVN
FLLRMDRAHEAKIRYYTYLIMNKGRLLKAGRQVREPGQDLVVLPLSITTD
FIPSFRLVAYYTLIGASGQREVVADSVWVDVKDSCVGSLVVKSGQSEDRQ
PVPGQQMTLKIEGDHGARVVLVAVDKGVFVLNKKNKLTQSKIWDVVEKAD
IGCTPGSGKDYAGVFSDAGLTFTSSSGQQTAQRAELQCPQ
3D structure
PDB7bag Insight into mode-of-action and structural determinants of the compstatin family of clinical complement inhibitors.
ChainA
Resolution2.0 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A G345 P347 S388 N390 T391 H392 L454 L455 R456 M457 R459 E462 R486 D491 L492 G343 P345 S386 N388 T389 H390 L452 L453 R454 M455 R457 E460 R484 D489 L490
BS02 CA A P505 D532 V533 D535 P503 D530 V531 D533
Gene Ontology
Molecular Function
GO:0004866 endopeptidase inhibitor activity

View graph for
Molecular Function
External links
PDB RCSB:7bag, PDBe:7bag, PDBj:7bag
PDBsum7bag
PubMed36127336
UniProtP01024|CO3_HUMAN Complement C3 (Gene Name=C3)

[Back to BioLiP]