Structure of PDB 7b80 Chain A

Receptor sequence
>7b80A (length=340) Species: 9606 (Homo sapiens) [Search protein sequence]
SLEARAALNQALEMKRQGKREKAQKLFMHALKMDPDFVDALTEFGIFSEE
DKDIIQADYLYTRALTISPYHEKALVNRDRTLPLVEEIDQRYFSIIDSKV
KKVMSIPKGNSALRRVMEETYYHHIYHTVAIEGNTLTLSEIRHILETRYA
VPGKSDEEQNEVIGMHAAMKYINTTLVSRIGSVTISDVLEIHRRVLGYVD
PVEAGRFRTTQVLVGHHIPPHPQDVEKQMQEFVQWLNSEEAMNLHPVEFA
ALAHYKLVYIAPFIDGNGRTSRLLMNLILMQAGYPPITIRKEQRSDYYHV
LEAANEGDVRPFIRFIAKCTETTLDTLLFATTEYSVALPE
3D structure
PDB7b80 Structures of a deAMPylation complex rationalise the switch between antagonistic catalytic activities of FICD.
ChainA
Resolution1.87 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.108: protein adenylyltransferase.
3.1.4.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 AMP A E234 V316 H319 V360 D367 N369 G370 Y399 L403 N407 E132 V214 H217 V258 D265 N267 G268 Y297 L301 N305
External links
PDB RCSB:7b80, PDBe:7b80, PDBj:7b80
PDBsum7b80
PubMed34408154
UniProtQ9BVA6|FICD_HUMAN Protein adenylyltransferase FICD (Gene Name=FICD)

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