Structure of PDB 7b2i Chain A

Receptor sequence
>7b2iA (length=366) Species: 10090 (Mus musculus) [Search protein sequence]
PKLSLIKVVNGCRLGKIQNLGDCTVDIPGCLLYTRTGSAPHLTHQTLRNI
HGVPGIAQLTLSSLAEHHEVLAEYKKGVGSFIGMPESLFYCSLHDPVTPG
PAGYVTSKSVSVWGFGGRVEMTVSKFMAIQEALQPDWFQCLSDGEASCSI
KRARKSVDRSLLFLDSCLRLQEESEVLQKSVIIGVIEGGDVMEERLRSAR
ETAKRPVGGFLLDGFQGVTETRLHLLSSVTAELPEDKPRLICGVSRPDEV
LECIERGVDLFESFFPYQVTERGCALTFTFDSFEINLKEKKYQEDFDPLV
RGCSCYCCKNHTRAYIHHLLMTNELLAGVLLMMHNFEHYFGFFCSIREAL
KNDTLAQLKELICRQM
3D structure
PDB7b2i Structural and Biochemical Investigation of the Heterodimeric Murine tRNA-Guanine Transglycosylase.
ChainA
Resolution1.65 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.4.2.29: tRNA-guanosine(34) preQ1 transglycosylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C351 C353 C356 H382 C303 C305 C308 H334
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0008479 tRNA-guanosine(34) queuine transglycosylase activity
GO:0016763 pentosyltransferase activity
GO:0042803 protein homodimerization activity
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
Biological Process
GO:0006400 tRNA modification
GO:0008033 tRNA processing
GO:0101030 tRNA-guanine transglycosylation
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005741 mitochondrial outer membrane
GO:0032473 cytoplasmic side of mitochondrial outer membrane
GO:0032991 protein-containing complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7b2i, PDBe:7b2i, PDBj:7b2i
PDBsum7b2i
PubMed35815944
UniProtB8ZXI1|QTRT2_MOUSE Queuine tRNA-ribosyltransferase accessory subunit 2 (Gene Name=Qtrt2)

[Back to BioLiP]