Structure of PDB 7b19 Chain A

Receptor sequence
>7b19A (length=750) Species: 44689 (Dictyostelium discoideum) [Search protein sequence]
ENPIHDRTSDYHKYLKVKQGDSDLFKLTVSDKRYIWYNPDPKERDSYECG
EIVSETSDSFTFKTVDGQDRQVKKDDANQRNPIKFDGVEDMSELSYLNEP
AVFHNLRVRYNQDLIYTYSGLFLVAVNPFKRIPIYTQEMVDIFKGRRRNE
VAPHIFAISDVAYRSMLDDRQNQSLLITGESGAGKTENTKKVIQYLASVA
GRVLEQQILQANPILEAFGNAKTTRNNNSSRFGKFIEIQFNSAGFISGAS
IQSYLLEKSRVVFQSETERNYHIFYQLLAGATAEEKKALHLAGPESFNYL
NQSGCVDIKGVSDSEEFKITRQAMDIVGFSQEEQMSIFKIIAGILHLGNI
KFEKGAGEGAVLKDKTALNAASTVFGVNPSVLEKALMEPRILAGRDLVAQ
HLNVEKSSSSRDALVKALYGRLFLWLVKKINNVLCQERKAYFIGVLDISG
FEIFKVNSFEQLCINYTNEKLQQFFNHHMFKLEQEEYLKEKINWTFIDFG
LDSQATIDLIDGRQPPGILALLDEQSVFPNATDNTLITKLHSHFSKKNAK
YEEPRFSKTEFGVTHYAGQVMYEIQDWLEKNKDPLQQDLELCFKDSSDNV
VTKLFNDPNIASRAKKGANFITVAAQYKEQLASLMATLEGGGNPHFVRCI
IPNNKQLPAKLEDKVVLDQLRCNGVLEGIRITRKGFPNRIIYADFVKRYN
VPRDAEDSQKATDAVLKHLNIDPEQYRFGITKIFFRAGQLARIEEAREQR
3D structure
PDB7b19 Unraveling a Force-Generating Allosteric Pathway of Actomyosin Communication Associated with ADP and P i Release.
ChainA
Resolution2.55 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 AD9 A N127 P128 S181 G182 G184 K185 T186 E187 N233 S236 S237 G457 N127 P128 S181 G182 G184 K185 T186 E187 N226 S229 S230 G450
BS02 MG A T186 S237 T186 S230
Gene Ontology
Molecular Function
GO:0003774 cytoskeletal motor activity
GO:0005524 ATP binding
GO:0051015 actin filament binding
Cellular Component
GO:0016459 myosin complex

View graph for
Molecular Function

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Cellular Component
External links
PDB RCSB:7b19, PDBe:7b19, PDBj:7b19
PDBsum7b19
PubMed33374308
UniProtP08799|MYS2_DICDI Myosin-2 heavy chain (Gene Name=mhcA)

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