Structure of PDB 7b0g Chain A

Receptor sequence
>7b0gA (length=737) Species: 71997 (Thermococcus gorgonarius) [Search protein sequence]
MILDTDYITEDGKPVIRIFKKENGEFKIDYDRNFEPYIYALLKDDSAIED
VKKITAERHGTTVRVVRAEKVKKKFLGRPIEVWKLYFTHPQDQPAIRDKI
KEHPAVVDIYEYDIPFAKRYLIDKGLIPMEGDEELKMLAFAIATLYHEGE
EFAEGPILMISYADEEGARVITWKNIDLPYVDVVSTEKEMIKRFLKVVKE
KDPDVLITYNGDNFDFAYLKKRSEKLGVKFILGREGSEPKIQRMGDRFAV
EVKGRIHFDLYPVIRRTINLPTYTLEAVYEAIFGQPKEKVYAEEIAQAWE
TGEGLERVARYSMEDAKVTYELGKEFFPMEAQLSRLVGQSLWDVSRSSTG
NLVEWFLLRKAYERNELAPNKPDERELARRRESYAGGYVKEPERGLWENI
VYLDFRSLYPSIIITHNVSPDTLNREGCEEYDVAPQVGHKFCKDFPGFIP
SLLGDLLEERQKVKKKMKATIDPIEKKLLDYRQRLIKILANSFYGYYGYA
KARWYCKECAESVTAWGRQYIETTIREIEEKFGFKVLYADTDGFFATIPG
ADAETVKKKAKEFLDYINAKLPGLLELEYEGFYKRGFFATKKKYAVIDEE
DKITTRGLKMVRRDWSEIAKETQARVLEAILKHGDVEEAVRIVKEVTEKL
SKYEVPPEQLVIYQPIPGTVISYIVPKGGDRAIPFDEFDPAKHKYDAGYY
IENQVLPAVERILRAFGYRKEDLRYQKTRQVGLGAWL
3D structure
PDB7b0g Structural Studies of HNA Substrate Specificity in Mutants of an Archaeal DNA Polymerase Obtained by Directed Evolution.
ChainA
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A K487 D540 D542 E580 K592 Y594 R606 M610 R613 K487 D540 D542 E580 K592 Y594 R606 M610 R613
BS02 dna A S348 G350 S383 Y384 A385 G386 G495 G498 Y499 K591 K593 S348 G350 S383 Y384 A385 G386 G495 G498 Y499 K591 K593
BS03 CTP A R406 R460 K464 K487 R406 R460 K464 K487
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0004527 exonuclease activity
Biological Process
GO:0006260 DNA replication
GO:0006261 DNA-templated DNA replication
GO:0071897 DNA biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:7b0g, PDBe:7b0g, PDBj:7b0g
PDBsum7b0g
PubMed33302546
UniProtP56689|DPOL_THEGO DNA polymerase (Gene Name=pol)

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