Structure of PDB 7awq Chain A

Receptor sequence
>7awqA (length=404) Species: 9606 (Homo sapiens) [Search protein sequence]
KKVQNITKEDVKSFLRRNALLLLTVLAVILGVVLGFLLRPYPLSPREVKY
FAFPGELLMRMLKMLILPLIVSSLITGLASLDAKASGRLGMRAVVYYMST
TIIAVVLGIILVLIIHKEVLDCFLDLARNIFPSNLVSAAFRSYSTTQEVE
GMNILGLVVFSMVFGFALGKMGEQGQLLVDFFNSLNEATMKLVAIIMWYA
PLGILFLIAGKIVQLGMYMVTVIVGLVIHGLIVLPLIYFLITRKNPFVFI
AGILQALITALGTSSSSATLPITFKCLEENNGVDKRITRFVLPVGATINM
DGTALYQAVAAIFIAQVNNGQIITISITATAASIGAAGIPQAGLVTMVIV
LTAVGLPTDDITLIIAVDWLLDRFRTMVNVLGDALGAGIVEHLSRKELEK
QDAE
3D structure
PDB7awq The ion-coupling mechanism of human excitatory amino acid transporters.
ChainA
Resolution3.65 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ASP A S343 S344 S345 T382 G422 I423 A426 G427 D456 R459 T460 N463 S264 S265 S266 T303 G338 I339 A342 G343 D372 R375 T376 N379
BS02 6Z6 A S116 G117 G120 A123 V124 Y127 M231 F235 F369 V373 S86 G87 G90 A93 V94 Y97 M162 F166 F290 V294
Gene Ontology
Molecular Function
GO:0015293 symporter activity
Cellular Component
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:7awq, PDBe:7awq, PDBj:7awq
PDBsum7awq
PubMed34747040
UniProtP43003;
Q15758|AAAT_HUMAN Neutral amino acid transporter B(0) (Gene Name=SLC1A5)

[Back to BioLiP]