Structure of PDB 7awm Chain A

Receptor sequence
>7awmA (length=412) Species: 9606 (Homo sapiens) [Search protein sequence]
AKKKVQNITKEDVKSFLRRNALLLLTVLAVILGVVLGFLLRPYPLSPREV
KYFAFPGELLMRMLKMLILPLIVSSLITGLASLDAKASGRLGMRAVVYYM
STTIIAVVLGIILVLIIHPEVLDCFLDLARNIFPSNLVSAAFRSYSTQEV
EGMNILGLVVFSMVFGFALGKMGEQGQLLVDFFNSLNEATMKLVAIIMWY
APLGILFLIAGKIVGGQLGMYMVTVIVGLVIHGLIVLPLIYFLITRKNPF
VFIAGILQALITALGTSSSSATLPITFKCLEENNGVDKRITRFVLPVGAT
INMDGTALYEAVAAIFIAQVNNYELDFGQIITISITATAASIGAAGIPQA
GLVTMVIVLTAVGLPTDDITLIIAVDWLLDRFRTMVNVLGDALGAGIVEH
LSRKELEKQDAE
3D structure
PDB7awm The ion-coupling mechanism of human excitatory amino acid transporters.
ChainA
Resolution3.25 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ASP A S344 S345 T382 G422 I423 A426 G427 D456 R459 T460 S268 S269 T306 G346 I347 A350 G351 D380 R383 T384
BS02 6Z6 A S116 G117 G120 A123 V124 Y127 M231 F235 F369 V373 S88 G89 G92 A95 V96 Y99 M163 F167 F293 V297
Gene Ontology
Molecular Function
GO:0015293 symporter activity
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:7awm, PDBe:7awm, PDBj:7awm
PDBsum7awm
PubMed34747040
UniProtP43003;
Q15758|AAAT_HUMAN Neutral amino acid transporter B(0) (Gene Name=SLC1A5)

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