Structure of PDB 7atu Chain A

Receptor sequence
>7atuA (length=276) Species: 9606 (Homo sapiens) [Search protein sequence]
MPHRIFGEVLGKGCFGQAIKVTHRETGEVMVMKELIRFDEETQRTFLKEV
KVMRCLEHPNVLKFIGVLYKRLNFITEYIKGGTLRGIIKSMDSQYPWSQR
VSFAKDIASGMAYLHSMNIIHRDLNSHNCLVRENKNVVVADFGLARLMYT
VVGNPYWMAPEMINGRSYDEKVDVFSFGIVLCEIIGRVNADPDYLPRTMD
FGLNVRGFLDRYCPPNCPPSFFPITVRCCDLDPEKRPSFVKLEHWLETLR
MHLAGHLPLGPQLEQLDRGFWETYRR
3D structure
PDB7atu The LIMK1 Kinase Domain Bound To LIJTF500025
ChainA
Resolution2.8 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) D460 N462 H464 N465 D478 N512
Catalytic site (residue number reindexed from 1) D123 N125 H127 N128 D141 N154
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 RXN A V366 K368 M388 V396 L397 F399 F411 T413 L451 H458 D478 F479 V31 K33 M53 V61 L62 F64 F74 T76 L114 H121 D141 F142
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:7atu, PDBe:7atu, PDBj:7atu
PDBsum7atu
PubMed
UniProtP53667|LIMK1_HUMAN LIM domain kinase 1 (Gene Name=LIMK1)

[Back to BioLiP]