Structure of PDB 7ats Chain A

Receptor sequence
>7atsA (length=275) Species: 9606 (Homo sapiens) [Search protein sequence]
SMPHRIFRPSDLIHGEVLGKGCFGQAIKVTHRETGEVMVMKELIRFDEET
QRTFLKEVKVMRCLEHPNVLKFIGVLYKDKRLNFITEYIKGGTLRGIIKS
MDSQYPWSQRVSFAKDIASGMAYLHSMNIIHRDLNSHNCLVRENKNVVVA
DFGPYWMAPEMINGRSYDEKVDVFSFGIVLCEIIGRVNADPDYLPRTMDF
GLNVRGFLDRYCPPNCPPSFFPITVRCCDLDPEKRPSFVKLEHWLETLRM
HLAGHLPLGPQLEQLDRGFWETYRR
3D structure
PDB7ats The LIMK1 Kinase Domain Bound To LIJTF500127
ChainA
Resolution2.8 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D460 N462 H464 N465 D478
Catalytic site (residue number reindexed from 1) D133 N135 H137 N138 D151
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 RXQ A L345 V366 M388 L397 F411 E414 Y415 I416 G419 T420 L467 D478 F479 L18 V39 M61 L70 F84 E87 Y88 I89 G92 T93 L140 D151 F152
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:7ats, PDBe:7ats, PDBj:7ats
PDBsum7ats
PubMed
UniProtP53667|LIMK1_HUMAN LIM domain kinase 1 (Gene Name=LIMK1)

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