Structure of PDB 7ase Chain A

Receptor sequence
>7aseA (length=483) Species: 5693 (Trypanosoma cruzi) [Search protein sequence]
MGFELPEIFVNAPFTWGPPPSEIEMDGMKVRLYQKTDAIAPSDWLEAMLD
QANETKQFTTVKDENRLKALRNLHAKERRHGPERRFVKHYQNARSHFANK
AKRNLTLLPDTVKVPTDVLIFAEFTQAELAKMQNLQDAPTVTDISLHNRP
LVYNNAMEKASCKTPIRLEETNKSEEFFARSTTVEDGTLRDILKKEAAGT
HPIVVTTDEVLALMMTCSRGLHPWHLEIFRYNRMVFISKTEKSNVEVQWV
GETADTLRRPVENDPNESERITNLAKESTKAFNAFVAQACLKTRYQMKCE
KNPFPDTQPRLYRYRRFVMHAETDDHYDIIVRCEIDAVQNDKYVRIFGLL
EQCADGVESEWRKTLDSQGAKWISDEYRRNAQKMSRWVCLCHLSGTLMKI
GFLSRSYRSNGTLDPNKHEVLATHTKDPGPLAAQLGIKVGNMWAIADAII
MAFLKQQDLSEALLVKKSGGQSIMLIEKMEDEE
3D structure
PDB7ase Structural Differences in Translation Initiation between Pathogenic Trypanosomatids and Their Mammalian Hosts.
ChainA
Resolution3.33 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna A E46 D50 R149 R294 Q296 C299 K301 N302 D306 E46 D50 R149 R294 Q296 C299 K301 N302 D306
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003743 translation initiation factor activity
Biological Process
GO:0006412 translation
GO:0006413 translational initiation
Cellular Component
GO:0005737 cytoplasm
GO:0005852 eukaryotic translation initiation factor 3 complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7ase, PDBe:7ase, PDBj:7ase
PDBsum7ase
PubMed33357443
UniProtQ4DCN0

[Back to BioLiP]