Structure of PDB 7amv Chain A

Receptor sequence
>7amvA (length=1248) Species: 502057 (Vaccinia virus GLV-1h68) [Search protein sequence]
AVISKVTYSLYDQKEINATDIIISHVKNDDDIGTVKDGRLGAMDGALCKT
CGKTELECFGHWGKVSIYKTHIVKPEFISEIIRLLNHICIHCGLLRSREP
YSDDINLKELSGHALRRLKDKILSKKKSCWNSECMQPYQKITFSKKKVCF
VNKLDDINVPNSLIYQKLISIHEKFWPLLEIHQYPANLFYTDYFPIPPLI
IRPAISNELTYLLGMIVKNCNLNADEQVIQKAVIEYDDIKIISNNTTSIN
LSYITSGKNNMIRSYIVARRKDQTARSVIGPSTSITVNEVGMPAYIRNTL
TEKIFVNAFTVDKVKQLLASNQVKFYFNKRLNQLTRIRKNKIHLLPGDWV
EVAVQEYTSIIFGRQPSLHRYNVIASSIRATEGDTIKISPGIANSQNADF
DGDEEWMILEQNPKAVIEQSILMYPTTLLKHDIHGAPVYGSIQDEIVAAY
SLFRIQDLCLDEVLNILGKYGREFDPKGKCKFSGKDIYTYLIGEKINYPG
LLKDGEIIANDVDSNFVVAMRHLSLAGLLSDHKSNVEGINFIIKSSYVFK
RYLSIYGFGVTFKDLRPNSTFTNKLEAINVEKIELIKEAYAKYLNDVRDG
KIVPLSKALEADYVESMLSNLTNLNIREIEEHMRQTLIDDPDNNLLKMAK
AGYKVNPTELMYILGTYGQQRIDGEPAETRVLGRVLPYYLPDSKDPEGRG
YILNSLTKGLTGSQYYFSMLVARSQSTDIVCETSRTGTLARKIIKKMEDM
VVDGYGQVVIGNTLIKYAANYTKILGSVCKPVDLIYPDESMTWYLEISAL
WNKIKQGFVYSQKQKLAKKTLAPFNFLVFVKPTTEDNAIKVKDLYDMIHN
VIDDVREKYFFTVSNIDFMEYIFLTHLNPSRIRITKETAITIFEKFYEKL
NYTLGGGTPIGIISAQVLSEKFTQQALSSFHTTEKSGAVKQKLGFNEFNN
LTNLSKNKTEIITLVSDDISKLQSVKINFEFVCLGELNPNITLRKETDKY
VVDIIVNRLYIKRAEITELVVEYMIERFISFSVIVKEWGMETFIEDEDNI
RFTVYLNFVEPEELNLSKFMMVLPGAANKGKISKFKIPISDYTGYDDFNQ
TKKLNKMTVELMNLKELGSFDLENVNVYPGVWNTYDIFGIEAAREYLCEA
MLNTYGEGFDYLYQPCDLLASLLCASYEPESVNKFKFGAASTLKRATFGD
NKALLNAALHKKSEPINDNSSCHFFSKVPNIGTGYYKYFIDLGLLMRM
3D structure
PDB7amv Structural basis of the complete poxvirus transcription initiation process.
ChainA
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.6: DNA-directed RNA polymerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A K127 K128 K126 K127
BS02 MG A D415 D417 D419 D399 D401 D403
BS03 ZN A C49 C59 H62 C48 C58 H61
BS04 ZN A C90 C130 C89 C129
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0016779 nucleotidyltransferase activity
Biological Process
GO:0006351 DNA-templated transcription
Cellular Component
GO:0000428 DNA-directed RNA polymerase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7amv, PDBe:7amv, PDBj:7amv
PDBsum7amv
PubMed34556871
UniProtQ1PIV1

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