Structure of PDB 7amg Chain A

Receptor sequence
>7amgA (length=102) Species: 9606 (Homo sapiens) [Search protein sequence]
PRTVMVNLNIHNRNSSDYYNRSTSPWNLHRNEDPERYPSVIWEAKCRHLG
CINADGNVDYHMNSVPIQQEILVLRREPPHCPNSFRLEKILVSVGCTCVT
PI
3D structure
PDB7amg Discovery of an Oral, Rule of 5 Compliant, Interleukin 17A Protein-Protein Interaction Modulator for the Potential Treatment of Psoriasis and Other Inflammatory Diseases.
ChainA
Resolution3.18 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 RMQ A Y62 P63 W67 Q94 E95 I96 L97 V98 L99 L112 Y37 P38 W42 Q69 E70 I71 L72 V73 L74 L87
Gene Ontology
Molecular Function
GO:0005125 cytokine activity
Biological Process
GO:0006954 inflammatory response
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Cellular Component
External links
PDB RCSB:7amg, PDBe:7amg, PDBj:7amg
PDBsum7amg
PubMed35767390
UniProtQ16552|IL17_HUMAN Interleukin-17A (Gene Name=IL17A)

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