Structure of PDB 7akn Chain A

Receptor sequence
>7aknA (length=316) Species: 1427 (Bacillus thermoproteolyticus) [Search protein sequence]
ITGTSTVGVGRGVLGDQKNINTTYSTYYYLQDNTRGNGIFTYDAKYRTTL
PGSLWADADNQFFASYDAPAVDAHYYAGVTYDYYKNVHNRLSYDGNNAAI
RSSVHYSQGYNNAFWNGSQMVYGDGDGQTFIPLSGGIDVVAHELTHAVTD
YTAGLIYQNESGAINEAISDIFGTLVEFYANKNPDWEIGEDVYTPGISGD
SLRSMSDPAKYGDPDHYSKRYTGTQDNGGVHINSGIINKAAYLISQGGTH
YGVSVVGIGRDKLGKIFYRALTQYLTPTSNFSQLRAAAVQSATDLYGSTS
QEVASVKQAFDAVGVK
3D structure
PDB7akn Thermolysin from Bacillus thermoproteolyticus
ChainA
Resolution2.46 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.24.27: thermolysin.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A D138 E177 D185 E187 E190 D138 E177 D185 E187 E190
BS02 CA A E177 N183 D185 E190 D191 E177 N183 D185 E190 D191
BS03 CA A D57 D59 Q61 D57 D59 Q61
BS04 CA A Y193 T194 I197 D200 Y193 T194 I197 D200
BS05 ZN A H142 H146 E166 H142 H146 E166
BS06 VAL A E143 R203 E143 R203
BS07 LYS A N111 N112 H231 N111 N112 H231
Gene Ontology
Molecular Function
GO:0004222 metalloendopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:7akn, PDBe:7akn, PDBj:7akn
PDBsum7akn
PubMed
UniProtP00800|THER_BACTH Thermolysin (Gene Name=npr)

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