Structure of PDB 7afu Chain A

Receptor sequence

>7afuA (length=357) Species: 9606 (Homo sapiens) [Search protein sequence]

SFEGQMAEYPTISIDRFDRENLRARAYFLSACHKDHMKGLRAPTLKRRLE
CSLKVYLYCSPVTKELLLTSPKYRFWKKRIISIEIETPTQISLVDEASGE
KEEIVVTLLPAGHCPGSVMFLFQGNNGTVLYTGDFRLAQGEAARMELLHS
GGRVKDIQSVYLDTTFCDPRFYQIPSREECLSGVLELVRSWITRSPYHVV
WLNCKAAYGYEYLFTNLSEELGVQVHVNKLDMFRNMPEILHHLTTDRNTQ
IHACRHPKAEEYFQWSKLPCGITSRNRIPLHIISIKPSTMWFGERSRKTN
VIVRTGESSYRACFSFHSSYSEIKDFLSYLCPVNAYPNVIPTTMDKVVEI
LKPLCRS

3D structure

PDB

7afu Structural and mechanistic insights into the Artemis endonuclease and strategies for its inhibition.

Chain

Resolution

1.56 Å

3D
structure

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Enzymatic activity