Structure of PDB 7ae6 Chain A

Receptor sequence
>7ae6A (length=147) Species: 1532906 (Aphanizomenon flos-aquae 2012/KM1/D3) [Search protein sequence]
NIEPVIIETRLELIGRYLDHLKKFENISLDDYLSSFEQQLITERLLQLIT
QAAIDINDHILSKLKSGKSYTNFEAFIELGKYQILTPELAKQIAPSSGLA
NRLVHEYDDIDPNQVFMAISFALQQYPLYVRQINSYLITLEEENDLE
3D structure
PDB7ae6 HEPN-MNT Toxin-Antitoxin System: The HEPN Ribonuclease Is Neutralized by OligoAMPylation.
ChainA
Resolution1.65 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.27.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 AMP A F75 P97 N103 Y109 F73 P95 N101 Y107
BS02 AMP A P97 L101 R104 D111 I112 D113 Q116 P95 L99 R102 D109 I110 D111 Q114
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0004519 endonuclease activity
GO:0004540 RNA nuclease activity
Cellular Component
GO:0110001 toxin-antitoxin complex

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Molecular Function
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Cellular Component
External links
PDB RCSB:7ae6, PDBe:7ae6, PDBj:7ae6
PDBsum7ae6
PubMed33290744
UniProtA0A0B0QJR1|HEPT_APHF2 tRNA nuclease HepT (Gene Name=hepT)

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