Structure of PDB 7abs Chain A

Receptor sequence
>7absA (length=359) Species: 9606 (Homo sapiens) [Search protein sequence]
SFEGQMAEYPTISIDRFDRENLRARAYFLSHCHKDHMKGLRAPTLKRRLE
CSLKVYLYCSPVTKELLLTSPKYRFWKKRIISIEIETPTQISLVDEASGE
KEEIVVTLLPAGHCPGSVMFLFQGNNGTVLYTGDFRLAQGEAARMELLHS
GGRVKDIQSVYLDTTFCDPRFYQIPSREECLSGVLELVRSWITRSPYHVV
WLNCKAAYGYEYLFTNLSEELGVQVHVNKLDMFRNMPEILHHLTTDRNTQ
IHACRHPKAEEYFQWSKLPCGITSRNRIPLHIISIKPSTMWFGERSRKTN
VIVRTGESSYRACFSFHSSYSEIKDFLSYLCPVNAYPNVIPVGTTMDKVV
EILKPLCRS
3D structure
PDB7abs Structural and mechanistic insights into the Artemis endonuclease and strategies for its inhibition.
ChainA
Resolution1.97 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A H35 K36 D37 H115 K207 A208 A209 H319 H33 K34 D35 H113 K205 A206 A207 H317
BS02 ZN A H228 H254 C256 C272 H226 H252 C254 C270
BS03 ZN A H33 H35 H115 D136 H31 H33 H113 D134
External links
PDB RCSB:7abs, PDBe:7abs, PDBj:7abs
PDBsum7abs
PubMed34387696
UniProtQ96SD1|DCR1C_HUMAN Protein artemis (Gene Name=DCLRE1C)

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